Fungal Infections (FI) Associated with Covid-19

The aim of this study was to conduct a survey of the fungal species associated with COVID-19 viral infection in 150 patients who were admitted to the intensive care unit (ICU) in Al-Diwaniyah Teaching Hospital in Al-Diwaniyah City, Iraq, for a five-month period from October 2021 to February 2022. The results indicated the dominance of Candida spp. over the rest of the isolated fungal species, with 97 isolates (64.66%). Aspergillus spp., with 15 isolates (10%), came in second. Rhizopus sp. with 2 isolates (1.33%). Then with 1 isolate (0.66%) for each of Penicillium sp., Coccidiodes sp., and Rhodotorula sp., Also, results show that the male has a higher percentage than the female (54.9%) and co-infections with fungi were more common in the 60-69 age group then in the 70-79 age group (34% versus 24%, respectively). Taking a deeper look at the patients' medical histories, it was shown that fungal co-infection was more prevalent in those with chronic sickness than in those without chronic disease (55.66% versus 43.14%, respectively).Copyright © RJPT All right reserved.

Control of black fungus associated with COVID-19 by some safety methods

Antibacterial, antifungal, and antiviral activities are all present in silver nanoparticles. Silver nanoparticles have the capacity to penetrate bacterial cell walls, altering cell membrane structure and even causing cell death. The efficiency of silver nanoparticles on the fungi that cause the black fungus linked with Covid was investigated in this study,The poisoned food technique was utilized with concentrations of 5%, 10%, and 20%, and while all of the concentrations were efficient, the effect was larger when the greatest concentration was employed.The efficacy of mushrooms was also tested against these fungi that cause mucormycosis,The antifungal activity of ethanol extracts of Agaricus bisporus against Rhizopus arrhizus was determined in vitro using the poison food approach and different concentrations of the extract (8, 10, 16 mg/ml). The maximum effect of ethanolic extract against Rhizopus arrhizus growth was achieved at 8 mg/ml, and the maximum effect of ethanolic extract was achieved at 16 mg/ml, with a growth rate of 57.5mm. © 2022 by the Author(s).

Morphological effects of alcoholic extract of mushroom and silver nanoparticles on black fungus

The present study aimed to know the extension effects of alcoholic extract of Agaricus bisporus in concentrations (16)mg\ml and silver nanoparticles (20)% on morphology (macro and microfeatures) of Rhizopus arrhizus that causes co infection (mucormycosis)in covid-19 patients .Results show ,decrease in the growth rate of the tested strains ,some parts hyphae was atrophied and increased lateral branching points and swelling of the cell wall and condensing the material cytoplasm and other changes. © 2022 by the Author(s).

Filamentous fungi associated with COVID-19 and its susceptibility to some antifungals

The purpose of this study was to conduct a survey of the fungal species associated with COVID-19 viral infection in 150 patients who were admitted to the intensive care unit (ICU) in Al-Diwaniyah Teaching Hospital in Al-Diwaniyah City, Iraq, for a period of five months beginning in October 2021 and ending in February 2022. The survey was to be conducted over the course of the period from October 2021 to February 2022. According to the findings, yeasts were more prevalent than any of the other detected fungal species, accounting for 98 of the total isolates (65.33 percent). While filamentous fungus accounted for 19 isolates (12.33 percent), including the predominance of Aspergillus flavus with 6 isolates (40 percent) in comparison to the Aspergillus spp. ratio, these fungi were found to be rather uncommon. In light of the fact that this publication provided evidence of the isolation of Aspergillus sydowii from COVID19 patients for the first time anywhere in the world: In addition, we drew attention to the outstanding activity of the antifungal medications amphotericin B, itraconazole, and voriconazole, all of which have a high susceptibility rate. © 2022 International Journal of Health Sciences.All rights reserved.

Pulmonary aspergillosis associated with covid-19

Among the potential pathogens in patients with COVID-19 that we should pay more attention to is Aspergillosis, as pulmonary Aspergillosis is a critical complication of patients with acute respiratory distress syndrome, especially those with severe pneumonia. In this study, Aspergillus sp. was isolated from patients with COVID-19 from the respiratory tract, and its presence was surveyed as a co-infection with a viral infection. The results showed that Aspergillosis constituted a relatively high percentage in patients 10.8% of the total infections, represented by four species (Aspergillus tamarii, Aspergillus flavus, Aspergillus candidus, and Aspergillus niger). Also, the most susceptible age to infection with co-infections is the elderly, where the age of more than 60 years, and that diabetes is the most risk factor for infection with Aspergillosis accompanying the virus. Males were also more susceptible to co-infection than females. © 2021, Dr. Yashwant Research Labs Pvt. Ltd.. All rights reserved.

A possible warning for covid-19 patients on complications of fungal infection: A review

New problems are emerging in the health sector as the global Coronavirus Disease 2019 (COVID-19) pandemic expands worldwide. The big global emergency is the need for effective testing tools, therapies, and vaccines for COVID-19. Although these targets are particularly important, the increasing risk of coinfections is a significant threat to health systems and patients’ lives. Although statistical data are still not adequately released, coinfections in patients with COVID-19 developed secondary systemic mycosis. Any of these significant results will be discussed in this review with the main objective of warning the population of the high risk of concomitant systemic mycosis in individuals with COVID-19 induced weakness.